Dr. Bhupesh Goyal
Assistant Professor
Specialization
Protein folding and misfolding, molecular modeling
bhupesh@thapar.edu
Protein folding and misfolding, molecular modeling
Bhupesh Goyal, Ph.D. |
Assistant Professor-III, School of Chemistry and Biochemistry Thapar Institute of Engineering & Technology (Deemed to be University) Patiala–147004, Punjab, India Email: bhupesh@iitbombay.org, bhupesh@thapar.edu; Mobile: 9988110514 |
EDUCATION
Degree |
Institute/University |
Year |
Result |
Ph.D. (Computational and Bioorganic Chemistry) |
Department of Chemistry, IIT Bombay, Mumbai |
2012 |
CPI 9.33 |
M.Sc. (Honours School) Chemistry |
Department of Chemistry, Panjab University, Chandigarh |
2006 |
73.7% |
B.Sc. (Honours School) Chemistry |
Department of Chemistry, Panjab University, Chandigarh |
2004 |
72.1% |
TEACHING AND RESEARCH EXPERIENCE
Name of the Institution |
Position |
From |
To |
Courses taught/ Research work |
Thapar Institute of Engineering & Technology, Patiala, Punjab |
Assistant Professor, School of Chemistry & Biochemistry |
2017 |
Continuing |
Chemical Biology, Stereochemistry and Photochemistry, Synthetic and Natural Polymers, Organic Reaction Mechanisms, Organic Chemistry, Applied Chemistry, Electrochemistry and Thermodynamics, Applied Chemistry Lab |
Sri Guru Granth Sahib World University Fatehgarh Sahib, Punjab |
Assistant Professor, Department of Chemistry |
2013 |
2017 |
Topics in Chemistry, Organic Reaction Mechanism & Stereochemistry, Organic Reactions & Rearrangements, Bioorganic Chemistry, Biochemistry, Applied Chemistry, Physical Chemistry lab, Applied Chemistry Lab |
Central University of Punjab, Bathinda, Punjab |
Assistant Professor (contractual), Centre for Computational Sciences |
2013 |
2013 |
Contributed in the drafting of syllabus for M.Sc. in Computational Sciences |
Arizona State University, Tempe, USA |
Postdoctoral Scholar, Department of Chemistry & Biochemistry |
2012 |
2013 |
Synthesis and characterization of membrane soluble peptides to study protein protein interactions in the membrane |
Indian Institute of Technology Bombay, Mumbai |
Teaching Assistant, Department of Chemistry |
2008 |
2009 |
B. Tech. Theory Course (CH-102 T) (Organic) & B. Tech. Laboratory Course (CH-117 L) |
Ranbaxy Research Laboratories, Gurgaon |
Trainee Chemist, Medicinal Chemistry Department |
2006 |
2007 |
Design and synthesis of biologically active small molecules using parallel synthesis |
RESEARCH PROJECTS SUBMITTED/RECEIVED IN THE PAST AND/ONGOING PROJECTS
AWARDS AND RECOGNITIONS
S. No. |
Name of Award |
Awarding Agency |
Year |
1. |
Selected for the best poster award on the topic “Identification of potential inhibitors against β2m aggregation in Dialysis-related amyloidosis by computational screening and molecular dynamics simulations” at 88th Annual Meeting of the Society of Biological Chemists, India (SBCI-2019) and conference on Advances at the Interface of Biology & Chemistry at BARC, Mumbai, Nov. 1- 3, 2019 |
Society of Biological Chemists (SBCI), India |
2019 |
2. |
Recognised by Royal Society of Chemistry editors as an Outstanding Reviewer for RSC Advances in 2018 |
Royal Society of Chemistry, UK |
2018 |
3. |
Nominated by Indian Science Congress Association (ISCA), Patiala-Chapter for a poster presentation on the topic entitled “Present scenario and recent developments in Alzheimer’s disease research” in the “Science Communicators Meet (9th Rastriya Vigyan Sancharak Sammelan) during 103rd Session of the Indian Science Congress” at University of Mysore, Mysuru, Jan 3–7, 2016 |
Indian Science Congress Association (ISCA), Patiala-Chapter |
2016 |
4. |
Invited Lecture on the topic “Understanding the role of molecular dynamics simulations in computer-aided drug design” during the 46th workshop entitled “Application of Molecular Dynamics Simulation in Molecular Modelling & Drug Designing”, at Biotech Park in Biotechnology City, Lucknow, promoted by Department of Biotechnology, Govt. of India and Department of Science & Technology, Govt. of U.P. during Feb 26–28, 2015 |
Biotech Park in Biotechnology City, Lucknow, promoted by Department of Biotechnology, Govt. of India and Department of Science & Technology, Govt. of U.P. |
2015 |
5. |
Selected for “Winter School on Computational Chemistry” conducted by UGC-Networking Resource Centre, School of Chemistry, University of Hyderabad during Dec 29, 2014–Jan 10, 2015 |
UGC-Networking Resource Centre, School of Chemistry, University of Hyderabad |
2015 |
6. |
Selected for the Science Academies Refresher Course on "Bioinformatics in Modern Biology" during May 5–17, 2014 at School of Life Sciences, Manipal University, Manipal. |
School of Life Sciences, Manipal University, Manipal |
2014 |
7. |
Awarded Start-Up Research Grant (Young Scientists) of Rs. 14.30 lakhs on the “Computational Scrutiny of the Mechanism of Amyloid β-Peptide Aggregation” by Science and Engineering Research Board (SERB), Govt. of India in March, 2014 |
Science and Engineering Research Board (SERB), Govt. of India |
2014 |
8. |
Awarded postdoctoral research fellowship at the Center for Bio-inspired Solar Fuel Production, an Energy Frontier Research Center sponsored by the U.S. Department of Energy, at Department of Chemistry & Biochemistry, Arizona State University, Tempe, USA during 2012-2013 |
U.S. Department of Energy, at Department of Chemistry & Biochemistry, Arizona State University, Tempe, USA |
2012 |
9. |
Awarded Foreign Travel Grant for a poster presentation in 242nd American Chemical Society National Meeting & Exposition, Denver, Colorado, USA during Aug. 28–Sept. 01, 2011 |
DST, New Delhi, CSIR, New Delhi & DBT, New Delhi |
2011 |
10. |
Awarded senior research fellowship by Council of Scientific & Industrial Research (CSIR), New Delhi in 2009 at Department of Chemistry, IIT Bombay, Mumbai. |
CSIR-UGC, New Delhi, India |
2009 |
11. |
Awarded junior research fellowship by Council of Scientific & Industrial Research (CSIR), New Delhi in 2007 at Department of Chemistry, IIT Bombay, Mumbai. |
CSIR-UGC, New Delhi, India |
2007 |
12. |
Summer visiting student-fellow of the Indian Academy of Sciences under the supervision of Prof. Y. D. Vankar, Department of Chemistry, IIT Kanpur, India. (May 2005 – July 2005) |
Indian Academy of Sciences |
2005 |
13. |
Rank 1 in B.Sc. (Honours School) IIIrd year at Department of Chemistry, Panjab University, Chandigarh, India |
Department of Chemistry, Panjab University, Chandigarh |
2004 |
14. |
Merit Certificate under National Scholarship Scheme in March 1998 |
Govt. of Punjab |
1998 |
PEER-REVIEWED PUBLICATIONS
Total Publications: 47; Citations (Google Scholar, 23-08-2023): 1051; h-index (Google Scholar, 23-08-2023): 16
Cumulative Impact Factor: 185.8; Avg. IF/publication: 4.0
S. No. |
Author(s) |
Title |
Name of Journal |
Vol |
Page |
Year |
Impact factor |
1. |
Kaur, G.; Goyal, B.* |
Insights into the interaction mechanism of boceprevir with SARS-CoV‑2 main protease |
ChemistrySelect |
8 |
e202301415 |
2023 |
2.1 |
2. |
Kaur, G.; Mankoo, O.K.; Goyal, D.*; Goyal, B.* |
Unveiling how hydroxytyrosol destabilizes α–Syn oligomers using molecular simulations |
Journal of Physical Chemistry B |
127 |
5620–5632 |
2023 |
3.3 |
3. |
Mann, S.; Kaur, A.; Kaur, A.; Priyadarshi, N.; Goyal, B.*; Singhal, N. K.*; Goyal, D.* |
Triazole–peptide conjugate as modulator of Aβ–aggregation, metal–mediated Aβ–aggregation and cytotoxicity |
ACS Chemical Neuroscience |
14 |
1631-1645 |
2023 |
5.0 |
4. |
Kaur, A.; Goyal, B.*
|
Identification of new pentapeptides as potential inhibitors of amyloid–β42 aggregation using virtual screening and molecular dynamics simulations
|
Journal of Molecular Graphics and Modelling |
124 |
108558 |
2023 |
2.9 |
5. |
Mankoo, O. K.; Kaur, A.; Goyal, D.*; Goyal, B.* |
Unravelling the destabilization potential of Ellagic acid on α-Synuclein fibrils using molecular dynamics simulations |
Physical Chemistry Chemical Physics |
25 |
8128–8143 |
2023 |
3.3 |
6. |
Gupta, R.; Singh, V.; Sarawagi, N.; Kaur, G.; Kaur, R.; Priyadarshi, N.; Rishi, V.; Goyal, B.*; Mishra, P. P.*; Singhal, N. K.* |
Salmonella typhimurium detection and ablation using OmpD specific aptamer with non-magnetic and magnetic graphene oxide |
Biosensors and Bioelectronics
|
234 |
115354 |
2023 |
12.6 |
7. |
Garg, P.; Priyadarshi, N.; Ambule, M.; Kaur, G.; Kaul, S.; Gupta, R.; Sagar, P.; Bajaj, G.; Yadav, B.; Rishi, V.*; Goyal, B.*; Srivastava, A. K.*; Singhal, N. K.* |
Multiepitope glycan based laser assisted fluorescent nanocomposite with dual functionality for sensing and ablation of Pseudomonas aeruginosa |
Nanoscale |
DOI: 10.1039/D3NR02983B |
2023 |
6.7 |
|
8. |
Kaur, R.; Narang, S. S.; Singh, P.; Goyal, B.* |
Structural and molecular insights into tacrine-benzofuran hybrid induced inhibition of amyloid-β peptide aggregation and BACE1 activity |
Journal of Biomolecular Structure and Dynamics |
DOI: 10.1080/07391102.2023.2191722 |
2023 |
4.4 |
|
9. |
Kaur, G.; Goyal, B.* |
Deciphering the molecular mechanism of inhibition of β-secretase (BACE1) activity by a 2-amino-imidazol-4-one derivative |
ChemistrySelect |
7 |
e202202561 |
2022 |
2.1 |
10. |
Singh, K.; Kaur, A.; Goyal, D.*; Goyal, B.* |
Mechanistic insights into the mitigation of Aß aggregation and protofibril destabilization by a D–enantiomeric decapeptide rk10 |
Physical Chemistry Chemical Physics |
24 |
21975– 21994 |
2022 |
3.3 |
11. |
Kaur, R.; Saini, R. K.; Singh, P.; Goyal, B.* |
Unveiling the inhibitory mechanism of peptidomimetic inhibitor against Aβ42 aggregation and protofibril disaggregation by molecular dynamics |
Journal of Molecular Liquids
|
335 |
116474 |
2021 |
6.0 |
12. |
Garg, M.; Kumar, S., Kaur, A.; Goyal, B.; Kumar, R.* |
Effect of imidazolium based ionic liquids on CO-association dynamics and thermodynamic stability of Ferrocytochrome c |
Biophysical Chemistry
|
268 |
106497 |
2021 |
3.8 |
13. |
Saini, R. K.; Goyal, D.*; Goyal, B.* |
Targeting human islet amyloid polypeptide aggregation and toxicity in type 2 diabetes: An overview of peptide-based inhibitors |
Chemical Research in Toxicology |
33
|
2719–2738 |
2020 |
4.1 |
14. |
Shuaib, S.; Saini, R. K.; Goyal, D.; Goyal, B.* |
Impact of K16A and K28A mutation on the structure and dynamics of amyloid-β42 peptide in Alzheimer's disease: Key insights from molecular dynamics simulations |
Journal of Biomolecular Structure and Dynamics |
38 |
708–721 |
2020 |
4.4 |
15. |
Narang, S. S.; Goyal, D.; Goyal, B.* |
Inhibition of Alzheimer's amyloid-β42 peptide aggregation by a bi-functional bistryptoline triazole: Key insights from molecular dynamics simulations |
Journal of Biomolecular Structure and Dynamics |
38 |
1598–1611 |
2020 |
4.4 |
16. |
Kaur, A.; Kaur, A.; Goyal, D.*; Goyal, B.* |
How does the mono-triazole derivative modulate Aβ42 aggregation and disrupt a protofibril structure: Insights from molecular dynamics simulations |
ACS Omega |
5 |
15606–15619 |
2020 |
4.1 |
17. |
Narang, S. S.; Shuaib, S.; Goyal, D.; Goyal, B.* |
In silico-guided identification of potential inhibitors against β2m aggregation in dialysis-related amyloidosis |
Journal of Biomolecular Structure and Dynamics |
38 |
3927–3941 |
2020 |
4.4 |
18. |
Kaur, A.; Goyal, B.* |
Deciphering the inhibitory mechanism of hIAPP-derived fragment peptide against hIAPP aggregation in type 2 diabetes |
ChemistrySelect |
5 |
13341–13350 |
2020 |
2.1 |
19. |
Kaur, A.; Goyal, D.*; Goyal, B.* |
An α-helix mimetic oligopyridylamide, ADH-31, modulates Aβ42 monomer aggregation and destabilizes protofibril structures: Insights from molecular dynamics simulations |
Physical Chemistry Chemical Physics
|
22 |
28055–28073 |
2020 |
3.3 |
20. |
Saini, R. K.; Shuaib, S.; Goyal, D.*; Goyal, B.* |
Impact of mutations on the conformational transition from α-helix to β-sheet structures in Arctic-type Aβ40: Insights from molecular dynamics |
ACS Omega |
5 |
23219–23228 |
2020 |
4.1 |
21. |
Goyal, B.*; Goyal, D.* |
Targeting the dimerization of the main protease of coronaviruses: A potential broad-spectrum therapeutic strategy |
ACS Combinatorial Science |
22 |
297–305 |
2020 |
3.903 |
22. |
Kaur, A.; Shuaib, S.; Goyal, D.*; Goyal, B.* |
Interactions of a multifunctional di-triazole derivative with Alzheimer’s Aβ42 monomer and Aβ42 protofibril: a systematic molecular dynamics study. |
Physical Chemistry Chemical Physics |
22 |
1543–1556 |
2020 |
3.3 |
23. |
Saini, R. K.; Thakur, H.; Goyal, B.* |
Journal of Molecular Graphics and Modelling |
97 |
107571 |
2020 |
2.9 |
|
24. |
Narang, S. S.; Goyal, D.; Goyal, B.* |
Molecular insights into the inhibitory mechanism of bi-functional bis-tryptoline triazole against β-secretase (BACE1) enzyme |
51 |
1593–1607 |
2019 |
3.5 |
|
25. |
Kaur, A.; Narang, S. S.; Kaur, A.; Mann, S.; Priyadarshi, N.; Goyal, B.*; Singhal, N. K.*; Goyal, D.* |
Multifunctional mono-triazole derivatives inhibit Aβ42 aggregation and Cu2+-mediated Aβ42 aggregation and protect against Aβ42-induced cytotoxicity |
Chemical Research in Toxicology |
32 |
1824–1839 |
2019 |
4.1 |
26. |
Kaur, A.; Mann, S.; Kaur, A.; Priyadarshi, N.; Goyal, B.*; Singhal, N. K.*; Goyal, D.* |
Multi-target-directed triazole derivatives as promising agents for the treatment of Alzheimer's disease |
Bioorganic Chemistry |
87 |
572–584 |
2019 |
5.1 |
27. |
Shuaib, S.; Narang, S. S.; Goyal, D.; Goyal, B.* |
Computational design and evaluation of β-sheet breaker peptides for destabilizing Alzheimer's amyloid-β42 protofibrils |
Journal of Cellular Biochemistry |
120 |
17935–17950 |
2019 |
4.0 |
28. |
Saini, R. K.; Shuaib, S.; Goyal, D.; Goyal, B.* |
Insights into the inhibitory mechanism of a resveratrol and clioquinol hybrid against Aβ42 aggregation and protofibril destabilization: A molecular dynamics simulation study |
Journal of Biomolecular Structure and Dynamics |
37 |
3183–3197 |
2019 |
4.4 |
29. |
Goyal, D.*; Kaur, A.; Goyal, B.* |
Benzofuran and indole: A promising scaffold for drug development in Alzheimer’s disease |
ChemMedChem |
13 |
1275–1299 |
2018 |
3.4 |
30. |
Saini, R. K.; Shuaib, S.; Goyal, D.; Goyal, B.* |
Molecular insights into the effect L17A/F19A double mutation on the structure and dynamics of Aβ40: A molecular dynamics simulation study |
Journal of Cellular Biochemistry |
119 |
8949–8961 |
2018 |
4.0 |
31. |
Shuaib, S.; Goyal, B.* |
Scrutiny of the mechanism of small molecule inhibitor preventing conformational transition of amyloid-β42 monomer: insights from molecular dynamics simulations |
Journal of Biomolecular Structure and Dynamics |
36 |
663–678 |
2018 |
4.4 |
32. |
Narang, S. S.; Shuaib, S.; Goyal, D.; Goyal, B.* |
Assessing the effect of D59P mutation in the DE loop region in amyloid aggregation propensity of β2-microglobulin: A molecular dynamics simulation study |
Journal of Cellular Biochemistry |
119 |
782–792 |
2017 |
4.0 |
33. |
Saini, R. K.; Shuaib, S.; Goyal, B.* |
Molecular insights into Aβ42 protofibril destabilization with a fluorinated compound D744: A molecular dynamics simulation study |
Journal of Molecular Recognition |
30 |
e2656 |
2017 |
2.7 |
34. |
Shuaib, S.; Saini, R. K.; Goyal, D.; Goyal, B.* |
Insights into the inhibitory mechanism of dicyanovinyl-substituted J147 derivative against Aβ42 aggregation and protofibril destabilization: A molecular dynamics simulation study |
ChemistrySelect |
2 |
1645–1657 |
2017 |
2.1 |
35. |
Goyal, D.*; Shuaib, S.; Mann, S.;, Goyal, B.* |
Rationally designed peptides and peptidomimetics as inhibitors of amyloid-β (Aβ) aggregation: potential therapeutics of Alzheimer's disease |
ACS Combinatorial Science |
19 |
55–80 |
2017 |
3.903 |
36. |
Narang, S. S.; Shuaib, S.; Goyal, B.* |
Molecular insights into the inhibitory mechanism of rifamycin SV against β2–microglobulin aggregation: A molecular dynamics simulation study |
International Journal of Biological Macromolecules |
102 |
1025–1034 |
2017 |
8.2 |
37. |
Srivastava, K. R.*; Goyal, B.; Kumar, A.; Durani, S. |
Scrutiny of electrostatic driven conformational ordering of polypeptide chain in DMSO: A study with model oligopeptide |
RSC Advances |
7 |
27981–27991 |
2017 |
3.9 |
38. |
Goyal, B.*; Srivastava, K. R.; Durani, S.* |
N-terminal diproline and charge group effects on the stabilization of helical conformation in alanine-based short peptides: CD studies with water and methanol as solvent |
Journal of Peptide Science |
23 |
431–437 |
2017 |
2.1 |
39. |
Goyal, B.*; Kumar, A.; Srivastava, K. R.; Durani, S.* |
Scrutiny of chain-length and N-terminal effects in α-helix folding: A molecular dynamics study on polyalanine peptides |
Journal of Biomolecular Structure and Dynamics |
35 |
1923–1935 |
2017 |
4.4 |
40. |
Goyal, B.*; Srivastava, K. R.; Durani, S.* |
Examination of the effect of N‐terminal diproline and charged side chains on the stabilization of helical conformation in alanine–based short peptides: A molecular dynamics study |
ChemistrySelect |
1 |
6321– 6327 |
2016 |
2.1 |
41. |
Goyal, B.*; Srivastava, K. Kumar, A.; R.; Patwari, G. N.; Durani, S.* |
Probing the role of electrostatics of polypeptide main-chain in protein folding by perturbing N-terminal residue stereochemistry: DFT study with oligoalanine models |
RSC Advances |
6 |
113611 – 113619 |
2016 |
3.9 |
42. |
Goyal, B.*; Kumar, A.; Srivastava, K. R.; Durani, S.* |
Computational scrutiny of the effect of N-terminal proline and residue stereochemistry in the nucleation of α-helix fold |
RSC Advances |
6 |
74162–74176 |
2016 |
3.9 |
43. |
Goyal, B.*; Srivastava, K. R.; Patel, K.; Durani, S.* |
Modulation of β-hairpin peptide self-assembly: A twenty-residue poly-L β-hairpin modified rationally as a mixed-L,D hydrolase |
ChemistrySelect |
1 |
2050–2057 |
2016 |
2.1 |
44. |
Goyal, B.*; Patel, K.; Srivastava, K. R.; Durani, S.* |
De novo design of stereochemically-bent sixteen-residue β-hairpin as a hydrolase mimic |
RSC Advances |
5 |
105400–105408 |
2015 |
3.9 |
45. |
Shinde, S.; Binder, J.; Goyal, B.; Woodrum, B.; Munari, S. D.; Levitus, M.*; Ghirlanda, G.* |
A designed buried salt bridge modulates heterodimerization of a membrane peptide |
Biopolymers |
106 |
437–443 |
2014 |
2.592 |
46. |
Srivastava, K. R.; Kumar, A.; Goyal, B.; Durani, S.* |
Stereochemistry and solvent role in protein folding: spectroscopic and molecular dynamics studies of poly-L and alternating-L,D homopolypeptides in DMSO |
The Journal of Physical Chemistry B |
115 |
6700–6708
|
2011 |
3.3 |
47. |
Patel, K.; Goyal, B.; Kumar, A.; Kishore, N.; Durani, S.* |
Cured of “stickiness”, poly-L β-hairpin is promoted with LL-to-DD mutation as a protein and a hydrolase mimic |
The Journal of Physical Chemistry B |
114 |
16887–16893
|
2010 |
3.3 |
BOOK CHAPTERS
Kaur, G.; Goyal, D.*; Goyal, B.* Computational modeling of MAO inhibitors as anti-Alzheimer agents. In Computational Modeling of Drugs Against Alzheimer’s Disease Edition 2, Roy, K., Ed.; Neuromethods, Springer, 2023, 203, pp 325–353.
Goyal, D.*; Goyal, B.* Solid phase peptide synthesis. In De Novo Peptide Design: Principles and Applications, Ist ed.; Ramakrishnan, V.; Patel, K.; Goyal, R., Eds.; Elsevier, 2022, pp 57–77.
LIST OF Ph.D. THESIS SUPERVISION
Name of Student |
Year of Completion |
Supervisor / Co-supervisor |
Title of Thesis |
Suniba Shuaib |
Ph.D. awarded (Oct. 2018) |
Supervisor |
Computational design of novel inhibitors against amyloid-β peptide aggregation Present affiliation: Biotech Analyst at SGS Canada, Mississauga, Ontario, Canada |
Simranjeet Singh Narang |
Ph.D. awarded (Sept. 2019) |
Supervisor |
In silico design of novel inhibitors against amyloidogenic fragments of human β2-microglobulin |
Anupamjeet Kaur |
Ph.D. awarded (Aug. 2022) |
Co-supervisor |
Design, synthesis and evaluation of multitarget directed ligands in Alzheimer’s disease treatment |
Rajdeep Kaur |
Ph.D. awarded (March 2023) |
Co-supervisor |
Computational studies of inhibitors against Aβ aggregation and β-secretase (BACE1) enzyme in Alzheimer's disease |
Rajneet Kaur Saini |
Ph.D. awarded (May 2023) |
Co-supervisor |
Molecular insight into the inhibitory mechanism of small molecules against Aβ aggregation and evaluation of novel inhibitors against Aβ aggregation in Alzheimer's disease |
Apneet Kaur |
Ongoing (Jan. 2018 onwards) |
Supervisor |
Computational design and evaluation of novel peptide inhibitors against amyloid aggregation in type 2 diabetes mellitus and Alzheimer’s disease |
Gurmeet Kaur |
Ongoing (July 2019 onwards) |
Supervisor |
Deciphering the inhibitory mechanism and in silico identification of potential inhibitors against BACE1 and SARS−CoV−2 Mpro enzymes |
Anisha |
Ongoing (July 2019 onwards) |
Supervisor |
Molecular insights into the inhibitory mechanism and in silico identification of potential small molecule inhibitors of hIAPP aggregation in T2D |
Tanishka |
Ongoing (July 2019 onwards) |
Supervisor |
Computational design and evaluation of peptide‒based antagonists of diabetes related human islet amyloid polypeptide aggregation |
Ishwar Dass Thakur |
Ongoing (July 2020 onwards) |
Supervisor |
Integrating in silico and in vitro studies to investigate potential inhibitors of Aβ and α-synuclein aggregation |
Arushi Dabas |
Ongoing (July 2020 onwards) |
Supervisor |
Rational design, synthesis and evaluation of destabilization potential of novel peptide inhibitors on amyloid-β fibrils |
Diksha |
Ongoing (Jan. 2021 onwards) |
Supervisor |
In vitro and in silico investigation of peptide-based inhibitors of human islet amyloid polypeptide (hIAPP) fibrillization in type 2 diabetes |
LIST OF KEY ACHIEVEMENT’S BY Ph.D. STUDENTS / AWARDS IN MENTORSHIP
PAPERS PRESENTED IN INTERNATIONAL/NATIONAL CONFERENCES
ADMINISTRATIVE DUTIES/ SYNERGISTIC ACTIVITIES
PERSONAL DETAILS
Nationality: Indian; Date of Birth: Oct 22, 1982; Sex: Male; Languages Known: English, Hindi, and Punjabi; Marital Status: Married
PROFESSIONAL MEMBERSHIPS
Life member of Indian Biophysical Society (IBS), Tata Institute of Fundamental Research, Mumbai, India; Indian Society of Chemists and Biologists (ISCB), CDRI-Lucknow, India; Indian Science Congress Association (ISCA), Kolkata, India; The Society of Biological Chemists India (SBCI), Indian Institute of Science, Bangalore, India; Chemical Research Society of India, Indian Institute of Science, Bangalore, India; Indian Peptide Society, Advanced Scientific Research (JNCASR), Bengaluru, India; Member of American Chemical Society, USA; Bioinformatics and Drug Discovery Society (BIDDS), Alagappa University, Karaikudi, India; Punjab Academy of Sciences, Punjabi University, Patiala, Punjab, India; IIT Bombay Alumini Association, IIT Bombay, Mumbai, India.